Introduction

The Synthon Chiragenics technology platform is based on a "chiral pool" approach in which the optical activity is derived primarily from carbohydrates. In this method for obtaining optically pure substances, a fragment containing the desired chiral center(s) and functionality is carved from an existing naturally occurring chemical feedstock. This resource of naturally occurring chiral feedstock is called the chiral pool. The chiral pool includes amino acids, carbohydrates, terpenes, lipids, and hydroxy acids among others.